ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2014, Vol. 45 ›› Issue (5): 809-814.doi: 10.11843/j.issn.0366-6964.2014.05.019

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Distribution of ER-α and ER-β in Nodose Ganglion of Female Goat

DONG Wei, XU Yong-ping*, JIN Xiu-fang, LI Qiang, CHEN Wen-dong, GUO Xiao   

  1. (College of Veterinary Medicine,Northwest A﹠F University,Yangling 712100, China)
  • Received:2013-10-10 Online:2014-05-23 Published:2014-05-23

Abstract:

The aim of this study was to explore whether the visceral sensory neurons in Nodose Ganglion (NG) were the major target cells of estrogen.Immunohistochemical SP method was adopted to observe the distribution of estrogen receptor (ER-α,β) in NG of female goats.The results indicated that all the nucleus of neurons was strong positive stained with brown to ER-α,β.While the cytoplasm of large-sized neurons showed medium positive with yellow and the cytoplasm of small and medium-sized neurons showed strong positive with claybank.In satellite cells,their medium positive expression was observed.Image analysis showed a significant difference of ER expression between neurons and non-neurons (P<0.01).The results showed that ER-α,β were expressed in NG,which indicate visceral sensory neurons in NG were the main target cells of estrogen.

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